Óxido nítrico exhalado, asma y atopia: análisis en un panel de niños en Santiago, Chile / Association of exhaled nitric oxide with asthma and atopy among children living in Santiago, Chile
Rev. méd. Chile
;
141(6): 743-750, jun. 2013. ilus, tab
Artículo
en Español
| LILACS
| ID: lil-687206
ABSTRACT
Background:
Chronic airway inflammation is a central process in asthma. Measurement of exhaled nitric oxide (eNO) is a non-invasive biomarker of eosinophilic airway inflammation.Aim:
To measure eNO levels in a population of asthmatic and non-asthmatic children and to evaluate their relationship with asthma and atopy. Material andMethods:
We studied 143 asthmatic and non-asthmatic children aged 6 to 14 years attended a hospital and primary health service. Participants were tested for allergies and followed during the winter months of 2010 and 2011. They were visited regularly at their homes and eNO levels were measured on each visit using a handheld equipment. Mean eNO distribution were compared by the presence of asthma or atopy using t-test and regression models.Results:
No significant differences for mean eNO levels were detected, according to presence of asthma or atopy, by any ofthe statistical methods used. Regression models showed significant effects for age but not for sex.Conclusions:
There were no differences in eNO levels in the studied children by the presence of asthma or atopy.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Asma
/
Óxido Nítrico
Tipo de estudio:
Factores de riesgo
Límite:
Adolescente
/
Niño
/
Child, preschool
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
America del Sur
/
Chile
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2013
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Chile
Institución/País de afiliación:
Hospital Roberto del Río/CL
Similares
MEDLINE
...
LILACS
LIS