Modulation of cerebral malaria by curcumin as an adjunctive therapy
Braz. j. infect. dis
; 17(5): 579-591, Sept.-Oct. 2013. ilus, tab
Article
en En
| LILACS
| ID: lil-689884
Biblioteca responsable:
BR1.1
ABSTRACT
Cerebral malaria is the most severe and rapidly fatal neurological complication of Plasmodium falciparum infection and responsible for more than two million deaths annually. The current therapy is inadequate in terms of reducing mortality or post-treatment symptoms such as neurological and cognitive deficits. The pathophysiology of cerebral malaria is quite complex and offers a variety of targets which remain to be exploited for better therapeutic outcome. The present review discusses on the pathophysiology of cerebral malaria with particular emphasis on scope and promises of curcumin as an adjunctive therapy to improve survival and overcome neurological deficits.
Palabras clave
Texto completo:
1
Índice:
LILACS
Asunto principal:
Adyuvantes Farmacéuticos
/
Malaria Cerebral
/
Curcumina
/
Antimaláricos
Límite:
Humans
Idioma:
En
Revista:
Braz. j. infect. dis
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
Año:
2013
Tipo del documento:
Article