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Urinary Symptoms and Urodynamics Findings in Patients with Friedreich's Ataxia
Musegante, Andre F. A.; Almeida, Priscila Natasja S.; Monteiro, Raphael Temporao M.; Barroso Jr, Ubirajara.
  • Musegante, Andre F. A.; Brasilia and Bahiana University of Bahia (UBjr). Salvador; SARAH Network of Rehabilitation Hospitals (RTMM). SARAH Network of Rehabilitation Hospitals (AFAM, PNSA). Salvador. BR
  • Almeida, Priscila Natasja S.; Brasilia and Bahiana University of Bahia (UBjr). Salvador; SARAH Network of Rehabilitation Hospitals (RTMM). SARAH Network of Rehabilitation Hospitals (AFAM, PNSA). Salvador. BR
  • Monteiro, Raphael Temporao M.; Brasilia and Bahiana University of Bahia (UBjr). Salvador; SARAH Network of Rehabilitation Hospitals (RTMM). SARAH Network of Rehabilitation Hospitals (AFAM, PNSA). Salvador. BR
  • Barroso Jr, Ubirajara; Brasilia and Bahiana University of Bahia (UBjr). Salvador; SARAH Network of Rehabilitation Hospitals (RTMM). SARAH Network of Rehabilitation Hospitals (AFAM, PNSA). Salvador. BR
Int. braz. j. urol ; 39(6): 867-874, Nov-Dec/2013. tab, graf
Artículo en Inglés | LILACS | ID: lil-699120
ABSTRACT
Purpose To assess the prevalence of LUTS, urinary tract and urodynamics changes in patients with Friedreich's Ataxia (FA), the most common form of hereditary ataxia. Materials and Methods This study evaluated 258 patients with genetically confirmed diagnoses of FA. Of the patients, 158 responded to a questionnaire which assessed their urinary symptoms. Patients with clinical changes underwent renal function examinations, ultrasound, and urodynamic studies (UDS). Results The sample analyzed showed that 82% of the patients complained of LUTS, although only 22% related the symptoms with quality of life impairment. Twenty eight (18%) of them agreed to undergo urodynamic evaluation. Urgency was the most common symptom. The exam was normal in 4 (14%) and detrusor underactivity was the most common finding. 14% (4 patients) presented with dilatation of the upper urinary tract at ultrasound scans. None of them had creatinine alterations. Conclusions LUTS was found in a large percentage of patients with FA, but only a few related it to their quality of life impairment. Although creatinine levels was normal in this sample, some patients may show upper urinary tract abnormalities, with deserves close observation and proper care. .
Asunto(s)


Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Urodinámica / Vejiga Urinaria / Ataxia de Friedreich / Síntomas del Sistema Urinario Inferior Tipo de estudio: Estudio diagnóstico / Estudio de prevalencia / Factores de riesgo Límite: Adulto / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: Int. braz. j. urol Asunto de la revista: Urología Año: 2013 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Brasilia and Bahiana University of Bahia (UBjr)/BR

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Texto completo: Disponible Índice: LILACS (Américas) Asunto principal: Urodinámica / Vejiga Urinaria / Ataxia de Friedreich / Síntomas del Sistema Urinario Inferior Tipo de estudio: Estudio diagnóstico / Estudio de prevalencia / Factores de riesgo Límite: Adulto / Femenino / Humanos / Masculino País/Región como asunto: America del Sur / Brasil Idioma: Inglés Revista: Int. braz. j. urol Asunto de la revista: Urología Año: 2013 Tipo del documento: Artículo País de afiliación: Brasil Institución/País de afiliación: Brasilia and Bahiana University of Bahia (UBjr)/BR