Anti dermatophytic therapy: prospects for the discovery of new drugs from natural products
Braz. j. microbiol
;
44(4): 1035-1041, Oct.-Dec. 2013. tab
Artículo
en Inglés
| LILACS
| ID: lil-705291
ABSTRACT
Millions of people and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes, which only infect keratinized structures. With the appearance of AIDS, the incidence of dermatophytosis has increased. Current drug therapy used for these infections is often toxic, long-term, and expensive and has limited effectiveness; therefore, the discovery of new anti dermatophytic compounds is a necessity. Natural products have been the most productive source for new drug development. This paper provides a brief review of the current literature regarding the presence of dermatophytes in immunocompromised patients, drug resistance to conventional treatments and new anti dermatophytic treatments.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Tiña
/
Productos Biológicos
/
Descubrimiento de Drogas
/
Antifúngicos
Límite:
Humanos
Idioma:
Inglés
Revista:
Braz. j. microbiol
Asunto de la revista:
Microbiologia
Año:
2013
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Estadual Paulista/BR
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