Puerperal brain cryptococcoma in an HIV-negative woman successfully treated with fluconazole: a case report
Rev. Soc. Bras. Med. Trop
;
47(2): 254-256, Mar-Apr/2014. graf
Artículo
en Inglés
| LILACS
| ID: lil-710359
ABSTRACT
Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus flucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV-negative woman diagnosed with a large cryptococcoma in the immediate postpartum period. The lesion was not resected, and due to amphotericin B intolerance, she received an extended course of fluconazole monotherapy. There was no disease recurrence during the 4 years of follow-up. The abrupt onset of her symptoms following delivery suggests that she developed a postpartum immune reconstitution syndrome. This case also demonstrates that in specific situations fluconazole monotherapy can be attempted in immunocompetent patients with cryptococcoma.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Infección Puerperal
/
Fluconazol
/
Meningitis Criptocócica
/
Antifúngicos
Tipo de estudio:
Estudio diagnóstico
Límite:
Adulto
/
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2014
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Estados Unidos
Institución/País de afiliación:
Yale School of Public Health/US
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