Vitiligo - Part 2 - classification, histopathology and treatment
An. bras. dermatol
;
89(5): 784-790, Sep-Oct/2014. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-720797
ABSTRACT
In an unprecedented effort in the field of vitiligo, a global consensus resulted on a suggested new classification protocol for the disease. The main histopathological finding in vitiligo is the total absence of functioning melanocytes in the lesions, while the inflammatory cells most commonly found on the edges of the lesions are CD4+ and CD8+ T lymphocytes. Physical and pharmacological treatment strategies aim to control the autoimmune damage and stimulate melanocyte migration from the unaffected edges of lesions and the outer hair follicle root sheath to the affected skin; moreover, surgical treatments can be combined with topical and physical treatments.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Vitíligo
Tipo de estudio:
Guía de Práctica Clínica
Límite:
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
An. bras. dermatol
Asunto de la revista:
Dermatologia
Año:
2014
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Santa Casa de Misericórdia Hospital/BR
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