Mandibular Branch of the Facial Nerve in Wistar Rats: New Experimental Model to Assess Facial Nerve Regeneration
Int. arch. otorhinolaryngol. (Impr.)
;
18(3): 277-282, Jul-Sep/2014.
Artículo
en Inglés
| LILACS
| ID: lil-720861
ABSTRACT
Introduction:
The ideal animal model for nerve regeneration studies is the object of controversy, because all models described by the literature have advantages and disadvantages.Objective:
To describe the histologic and functional patterns of the mandibular branch of the facial nerve of Wistar rats to create a new experimental model of facial nerve regeneration.Methods:
Forty-two male rats were submitted to a nerve conduction test of the mandibular branch to obtain the compound muscle action potential. Twelve of these rats had the mandibular branch surgically removed and submitted to histologic analysis (number, partial density, and axonal diameter) of the proximal and distal segments.Results:
There was no statistically significant difference in the functional and histologic variables studied.Conclusion:
These new histologic and functional standards of the mandibular branch of the facial nerve of rats establish an objective, easy, and greatly reproducible model for future facial nerve regeneration studies...
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Nervio Facial
/
Mandíbula
/
Regeneración Nerviosa
Tipo de estudio:
Estudio pronóstico
Límite:
Animales
Idioma:
Inglés
Revista:
Int. arch. otorhinolaryngol. (Impr.)
Asunto de la revista:
Otorrinolaringologia
Año:
2014
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade de São Paulo/BR
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