Molecular typing of Mycobacterium bovis isolates: a review
Braz. j. microbiol
;
45(2): 365-372, Apr.-June 2014. ilus, tab
Artículo
en Inglés
| LILACS
| ID: lil-723108
ABSTRACT
Mycobacterium bovis is the main causative agent of animal tuberculosis (TB) and it may cause TB in humans. Molecular typing of M. bovis isolates provides precise epidemiological data on issues of inter- or intra-herd transmission and wildlife reservoirs. Techniques used for typing M. bovis have evolved over the last 2 decades, and PCR-based methods such as spoligotyping and mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) have been extensively used. These techniques can provide epidemiological information about isolates of M. Bovis that may help control bovine TB by indicating possible links between diseased animals, detecting and sampling outbreaks, and even demonstrating cases of laboratory cross-contamination between samples. This review will focus on techniques used for the molecular typing of M. bovis and discuss their general aspects and applications.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Tipificación Molecular
/
Mycobacterium bovis
Límite:
Animales
/
Humanos
Idioma:
Inglés
Revista:
Braz. j. microbiol
Asunto de la revista:
Microbiologia
Año:
2014
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal de Pelotas/BR
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