Laparoscopic guided local injection in the X-linked muscular dystrophy mouse (mdx) diaphragm. An advance in experimental therapies for Duchenne Muscular Dystrophy
Acta cir. bras
;
29(11): 715-720, 11/2014. graf
Artículo
en Inglés
| LILACS
| ID: lil-728648
ABSTRACT
PURPOSE:
To investigate the development of a laparoscopy technique for local injection into the X-linked muscular dystrophy (mdx) diaphragm.METHODS:
It was used 10 mice Balb/C57 and 5 mdx mice and three differents decubitus type were tested the right lateral, supine, and supine decubitus with 20 degrees elevation of the forelimb. Abdominal caudal face and the 10 intercostal space were tested as spot to introduce the needle into the diaphragm.RESULTS:
Supine position with elevation of 20 degrees forelimb and the 10th intercostal space are the beneficial position to apply a local injection.CONCLUSION:
It was proved to be possible to perform the laparoscopy technique in the X-linked muscular dystrophy diaphragm and this requires a specific position and technique during the surgery. .
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Insuficiencia Respiratoria
/
Diafragma
/
Laparoscopía
/
Distrofia Muscular de Duchenne
/
Inyecciones Intramusculares
/
Distrofia Muscular Animal
Tipo de estudio:
Estudio de etiología
/
Estudio pronóstico
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2014
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
University of Sao Paulo/BR
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