Association between allergic responses and Schistosoma mansoni infection in residents in a low-endemic setting in Brazil
Rev. Soc. Bras. Med. Trop
;
47(6): 770-774, Nov-Dec/2014. graf
Artículo
en Inglés
| LILACS
| ID: lil-732977
ABSTRACT
Introduction Schistosomiasis is endemic in 76 countries and territories. Several studies have found an inverse correlation between parasitic disease and the development of allergies. The purpose of the present study was to determine whether infection with Schistosoma mansoni in subjects with a low parasite load is protective against allergy. The final sample consisted of 39 S. mansoni-positive and 52 S. mansoni-negative residents of a small community in northeastern Brazil. Methods All subjects were submitted to the Kato-Katz test, anti-S. mansoni IgG measurement, the prick test for aeroallergens, eosinophil counts and serum IgE measurement. Results Subjects who reacted to one or more antigens in the prick test were considered allergic. Only 7 S. mansoni-positive subjects (17.9%) reacted to one or more antigens, whereas 20 S. mansoni-negative subjects (38.5%) tested positive for allergy. Conclusions Our findings suggest that, in areas of low endemicity, infection with S. mansoni significantly reduces the risk of the development of allergy in subjects with a low parasite load. .
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LILACS (Américas)
Asunto principal:
Schistosoma mansoni
/
Esquistosomiasis mansoni
/
Anticuerpos Antihelmínticos
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Alérgenos
/
Hipersensibilidad Inmediata
/
Antígenos Helmínticos
Tipo de estudio:
Estudio observacional
/
Factores de riesgo
Límite:
Animales
/
Humanos
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
Medicina Tropical
Año:
2014
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Universidade Federal do Ceará/BR
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