Full-genome sequences of hepatitis B virus subgenotype D3 isolates from the Brazilian Amazon Region
Mem. Inst. Oswaldo Cruz
;
110(1): 151-153, 03/02/2015. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-741612
ABSTRACT
The Brazilian Amazon Region is a highly endemic area for hepatitis B virus (HBV). However, little is known regarding the genetic variability of the strains circulating in this geographical region. Here, we describe the first full-length genomes of HBV isolated in the Brazilian Amazon Region; these genomes are also the first complete HBV subgenotype D3 genomes reported for Brazil. The genomes of the five Brazilian isolates were all 3,182 base pairs in length and the isolates were classified as belonging to subgenotype D3, subtypes ayw2 (n = 3) and ayw3 (n = 2). Phylogenetic analysis suggested that the Brazilian sequences are not likely to be closely related to European D3 sequences. Such results will contribute to further epidemiological and evolutionary studies of HBV.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Transducción de Señal
/
Movimiento Celular
/
Carcinoma Hepatocelular
/
Inhibidor Tisular de Metaloproteinasa-1
/
Metaloproteinasa 9 de la Matriz
/
Neoplasias Hepáticas
Límite:
Humanos
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
2015
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Fiocruz/BR
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