Mast cell concentration and skin wound contraction in rats treated with Brazilian pepper essential oil (Schinus terebinthifolius Raddi)
Acta cir. bras
;
30(4): 289-295, 04/2015. graf
Artículo
en Inglés
| LILACS
| ID: lil-744280
ABSTRACT
PURPOSE:
To evaluate wound contraction and the concentration of mast cells in skin wounds treated with 5% BPT essential oil-based ointment in rats.METHODS:
Twenty rats, male, of adult age, were submitted to skin surgery on the right (RA) and left antimeres (LA) of the thoracic region. They were divided into two groups control (RA - wounds receiving daily topical application of vaseline and lanolin) and treated (LA - wounds treated daily with the topical ointment). The skin region with wounds were collected at days 4, 7, 14 and 21 after surgery. Those were fixed in 10% formaldehyde and later processed for paraffin embedding. Sections were obtained and stained by H.E for histopathology analysis. The degree of epithelial contraction was measured and mast cell concentration were also evaluated.RESULTS:
The treated group showed higher mast cell concentrations (p<0.05) associated with increased contraction at day 7 and 14 respectively.CONCLUSION:
Ointment containing 5% Brazilian pepper tree oil increases mast cell concentration and promotes skin wound contraction in rats. .
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Piel
/
Cicatrización de Heridas
/
Aceites Volátiles
/
Anacardiaceae
/
Mastocitos
/
Fitoterapia
Tipo de estudio:
Estudios de evaluación
Límite:
Animales
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2015
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
UFRPE/BR
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