Actualización en el diagnóstico y manejo del daño hepático agudo grave en el embarazo / Causes and management of severe acute liver damage during pregnancy
Rev. méd. Chile
;
143(5): 627-636, tab
Artículo
en Español
| LILACS
| ID: lil-751709
ABSTRACT
Abnormalities in liver function tests appear in 3% of pregnancies. Severe acute liver damage can be an exclusive condition of pregnancy (dependent or independent of pre-eclampsia) or a concomitant disease. HELLP syndrome and acute fatty liver of pregnancy are the most severe liver diseases associated with pregnancy. Both appear during the third trimester and have a similar clinical presentation. Acute fatty liver may be associated with hypoglycemia and HELLP syndrome is closely linked with pre-eclampsia. Among concomitant conditions, fulminant acute hepatitis caused by medications or virus is the most severe disease. Its clinical presentation may be hyper-acute with neurological involvement and severe coagulation disorders. It has a high mortality and patients should be transplanted. Fulminant hepatic failure caused by acetaminophen overdose can be managed with n-acetyl cysteine. Because of the high fetal mortality rate, the gestational age at diagnosis is crucial.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Complicaciones del Embarazo
/
Fallo Hepático Agudo
/
Síndrome HELLP
/
Hígado Graso
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
Límite:
Femenino
/
Humanos
/
Embarazo
Idioma:
Español
Revista:
Rev. méd. Chile
Asunto de la revista:
Medicina
Año:
2015
Tipo del documento:
Artículo
País de afiliación:
Chile
Institución/País de afiliación:
Hospital Clínico Universidad de Chile/CL
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