Behavioral effects of neurotensin applied to periventricular structures of rats
Braz. j. med. biol. res
;
22(6): 711-5, June 1989. ilus
Artículo
en Inglés
| LILACS
| ID: lil-75176
ABSTRACT
Neurotensin (NT), n active neuropeptide, and bicuculline, a GABA-A receptor antagonist, were microinjected into the rat hypothalaamus (MH) or the dorsal periaqueductal gray matter (DPAG). Bicuculline (80 pmol) produced behavioral activation which included jumping and NT (1-20 nmol) caused a dose-dependent behavioral activation accompanied by catalepsy rather than jumping. These results suggest that the behavioral activation produced by NT may be due to an interaction of the neuropeptide with specific receptors while its cataleptic effect may be attributed to the blockade of dopamine receptors
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Índice:
LILACS (Américas)
Asunto principal:
Conducta Fugitiva
/
Bicuculina
/
Neurotensina
/
Sustancia Gris Periacueductal
/
Hipotálamo Medio
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
1989
Tipo del documento:
Artículo
/
Congreso y conferencia
/
Documento de proyecto
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