Striatal dopamine receptor supersensitivity afte long-term haloperiodol treatment of hypophysectomized rats
Braz. j. med. biol. res
;
22(6): 741-3, June 1989. tab
Artículo
en Inglés
| LILACS
| ID: lil-75215
ABSTRACT
Dopamine (DA) receptor sensitivity was studied after long-term treatment with haloperidol (0.5 ad 3.0 mg/Kg, ip, single daily dose) or saline in hypophysectomized and infact rats. Haloperidol treatment for seven days produced a 25 to 125% increase in [3H]-spiroperidol binding to strial DA receptors in a dose-dependent fashion. The increase in binding sits (Bmax) was ximilar in both hypophysectomized and intact rats when compared to controls. The present results show that haloperidol treatment
Buscar en Google
Índice:
LILACS (Américas)
Asunto principal:
Receptores Dopaminérgicos
/
Cuerpo Estriado
/
Haloperidol
/
Hipofisectomía
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
1989
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS