Dapsone in the treatment of pemphigus vulgaris: adverse effects and its importance as a corticosteroid sparing agent
An. bras. dermatol
;
90(3,supl.1): 51-54, May-June 2015. ilus
Artículo
en Inglés
| LILACS
| ID: lil-755788
ABSTRACT
Pemphigus vulgaris is an autoimmune disease characterized by suprabasal blisters with acantholysis, which has a fatal course in a large number of untreated patients. Systemic corticosteroid therapy is considered first-line therapy. Adjuvant treatment with the goal of sparing corticosteroids include, among others, dapsone. This drug is not without side effects and its use requires clinical and laboratory control. We present a patient with PV initially managed with suboptimal dose of prednisone, evolving into drug-induced hepatitis after introduction of dapsone.
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Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Prednisona
/
Pénfigo
/
Dapsona
/
Antagonistas del Ácido Fólico
/
Glucocorticoides
Tipo de estudio:
Estudio de etiología
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
An. bras. dermatol
Asunto de la revista:
Dermatologia
Año:
2015
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Santa Casa da Misericórdia do Rio de Janeiro/BR
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