Parainfluenza virus as a cause of acute respiratory infection in hospitalized childrens
Braz. j. infect. dis
;
19(4): 358-362, July-Aug. 2015. tab, ilus
Artículo
en Inglés
| LILACS
| ID: lil-759284
ABSTRACT
Background:
Human parainfluenza viruses account for a significant proportion of lower respiratory tract infections in children.Objective:
To assess the prevalence of Human parainfluenza viruses as a cause of acute respiratory infection and to compare clinical data for this infection against those of the human respiratory syncytial virus.Methods:
A prospective study in children younger than five years with acute respiratory infection was conducted. Detection of respiratory viruses in nasopharyngeal aspirate samples was performed using the indirect immunofluorescence reaction. Length of hospital stay, age, clinical history and physical exam, clinical diagnoses, and evolution (admission to Intensive Care Unit or general ward, discharge or death) were assessed. Past personal (premature birth and cardiopathy) as well as family (smoking and atopy) medical factors were also assessed.Results:
A total of 585 patients were included with a median age of 7.9 months and median hospital stay of six days. No difference between the HRSV+ and HPIV+ groups was found in terms of age, gender or length of hospital stay. The HRSV+ group had more fever and cough. Need for admission to the Intensive Care Unit was similar for both groups but more deaths were recorded in the HPIV+ group. The occurrence of parainfluenza peaked during the autumn in the first two years of the study.Conclusion:
Parainfluenza was responsible for significant morbidity, proving to be the second-most prevalent viral agent in this population after respiratory syncytial virus. No difference in clinical presentation was found between the two groups, but mortality was higher in the HPIV+ group.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Infecciones por Respirovirus
/
Infecciones del Sistema Respiratorio
/
Infecciones por Virus Sincitial Respiratorio
/
Virus de la Parainfluenza 1 Humana
Tipo de estudio:
Estudio observacional
/
Factores de riesgo
Límite:
Child, preschool
/
Femenino
/
Humanos
/
Lactante
/
Masculino
País/Región como asunto:
America del Sur
/
Brasil
Idioma:
Inglés
Revista:
Braz. j. infect. dis
Asunto de la revista:
Enfermedades Transmisibles
Año:
2015
Tipo del documento:
Artículo
País de afiliación:
Brasil
Institución/País de afiliación:
Santa Casa de São Paulo/BR
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