Body mass index and comorbidity are associated with postoperative renal function after nephrectomy
Int. braz. j. urol
;
41(4): 697-706, July-Aug. 2015. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-763054
ABSTRACT
ABSTRACTPurpose:
To explore the association of body mass index (BMI) and comorbidity with renal function after nephrectomy.Materials andMethods:
We retrospectively analyzed 263 patients submitted to partial or radical nephrectomy from 2000-2013. Variables assessed included BMI, Charlson Comorbidity Index (CCI), race, tobacco use, tumor histology, surgical approach, Fuhrman nuclear grade, and tumor (T) classification. Glomerular filtration rate (GFR) was estimated using the Cockroft-Gault equation, adjusted for gender. Logistic regression was performed and included all interaction terms.Results:
Median follow-up was 19.6 months (IQR 5.2, 53.7). Median preoperative GFR was 86.2mL/min/1.73m2 and median postoperative GFR was 68.4mL/min/1.73m2. BMI (OR 1.07, 95%CI 1.02-1.11), CCI (OR 1.19, 95%CI 1.04-1.37), and radical nephrectomy (OR 3.09, 95%CI 1.51-6.33) were significantly associated with a decline in renal function of ≥25%.Conclusion:
BMI and CCI are associated with postoperative decline in renal function after nephrectomy. Additionally, radical nephrectomy is significantly associated with decreasing renal function compared to partial nephrectomy. These findings highlight the importance of assessing patient comorbidity in the decision making process for patients presenting with a renal mass.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Carcinoma de Células Renales
/
Índice de Masa Corporal
/
Recuperación de la Función
/
Neoplasias Renales
/
Nefrectomía
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Anciano
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Int. braz. j. urol
Asunto de la revista:
Urología
Año:
2015
Tipo del documento:
Artículo
País de afiliación:
Estados Unidos
Institución/País de afiliación:
Georgia Regents University/US
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