Primary adenocarcinoma of the colon with metastases to the mandible and liver: a case report / Adenocarcinoma primario de colon con metástasis en mandíbula e hígado: reporte de un caso
Int. j. odontostomatol. (Print)
; 9(2): 307-312, ago. 2015. ilus
Article
en En
| LILACS
| ID: lil-764046
Biblioteca responsable:
CL1.1
ABSTRACT
Metastatic lesions to the mandible may be originated from primary tumors elsewhere in the body. However, metastatic colonic carcinomas to this bone have been described infrequently. We report the case of a 71-year-old man with an adenocarcinoma in the sigmoid colon with liver metastasis. The patient underwent chemotherapy with indication of sigmoidectomy and retroperitoneal lymphadenectomy. One year and four months after the first metastatic diagnosis, the patient presented a tumor mass in the body and branch of the right mandible. Histopathological and immunohistochemical analysis with monoclonal antibodies specific for CEA, CK20, CDX-2, and vilin were compatible with the diagnosis of moderately differentiated metastatic adenocarcinoma with colonic origin. However, due to the wide spread of the disease, the patient died four months later. Tumor markers have been applied in clinical practice to assist in the diagnosis and to help guide prognosis, staging and treatment of cancer. The management of metastatic lesions remains a controversial issue and the development of new and more specific markers of gastrointestinal differentiation that may promote early diagnosis, are of continuous interest.
Palabras clave
Texto completo:
1
Índice:
LILACS
Asunto principal:
Adenocarcinoma
/
Neoplasias Mandibulares
/
Neoplasias del Colon
Tipo de estudio:
Prognostic_studies
/
Screening_studies
Límite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Int. j. odontostomatol. (Print)
Asunto de la revista:
ODONTOLOGIA
Año:
2015
Tipo del documento:
Article