Whole-body vibration improves fracture healing and bone quality in rats with ovariectomy-induced osteoporosis
Acta cir. bras
; 30(11): 727-735, Nov. 2015. tab, graf
Article
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| ID: lil-767596
Biblioteca responsable:
BR1.1
ABSTRACT
PURPOSE:
To investigate the effect of vibration therapy on the bone callus of fractured femurs and the bone quality of intact femurs in ovariectomized rats.METHODS:
Fifty-six rats aged seven weeks were divided into four groups control with femoral fracture (CON, n=14), ovariectomized with femoral fracture (OVX, n=14), control with femoral fracture plus vibration therapy (CON+VT, n=14), and ovariectomized with femoral fracture plus vibration therapy (OVX+VT, n=14). Three months after ovariectomy or sham surgery, a complete fracture was produced at the femoral mid-diaphysis and stabilized with a 1-mm-diameter intramedullary Kirschner wire. X-rays confirmed the fracture alignment and fixation. Three days later, the VT groups underwent vibration therapy (1 mm, 60 Hz for 20 minutes, three times per week for 14 or 28 days). The bone and callus quality were assessed by densitometry, three-dimensional microstructure, and mechanical test.RESULTS:
Ovariectomized rats exhibited a substantial loss of bone mass and severe impairment in bone microarchitecture, both in the non-fractured femur and the bone callus. Whole-body vibration therapy exerted an important role in ameliorating the bone and fracture callus parameters in the osteoporotic bone.CONCLUSION:
Vibration therapy improved bone quality and the quality of the fracture bone callus in ovariectomized rats.Palabras clave
Texto completo:
1
Índice:
LILACS
Asunto principal:
Osteoporosis
/
Vibración
/
Callo Óseo
/
Ovariectomía
/
Curación de Fractura
/
Fracturas del Fémur
Tipo de estudio:
Etiology_studies
/
Evaluation_studies
Límite:
Animals
Idioma:
En
Revista:
Acta cir. bras
Asunto de la revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2015
Tipo del documento:
Article