Autoimmune central diabetes insipidus in a patient with ureaplasma urealyticum infection and review on new triggers of immune response
Arch. endocrinol. metab. (Online)
;
59(6): 554-558, Dec. 2015. tab
Artículo
en Inglés
| LILACS
| ID: lil-767928
ABSTRACT
Diabetes insipidus is a disease in which large volumes of dilute urine (polyuria) are excreted due to vasopressin (AVP) deficiency [central diabetes insipidus (CDI)] or to AVP resistance (nephrogenic diabetes insipidus). In the majority of patients, the occurrence of CDI is related to the destruction or degeneration of neurons of the hypothalamic supraoptic and paraventricular nuclei. The most common and well recognized causes include local inflammatory or autoimmune diseases, vascular disorders, Langerhans cell histiocytosis (LCH), sarcoidosis, tumors such as germinoma/craniopharyngioma or metastases, traumatic brain injuries, intracranial surgery, and midline cerebral and cranial malformations. Here we have the opportunity to describe an unusual case of female patient who developed autoimmune CDI following ureaplasma urealyticum infection and to review the literature on this uncommon feature. Moreover, we also discussed the potential mechanisms by which ureaplasma urealyticum might favor the development of autoimmune CDI.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Enfermedades Autoinmunes
/
Ureaplasma urealyticum
/
Infecciones por Ureaplasma
/
Artritis Reactiva
/
Diabetes Insípida Neurogénica
Tipo de estudio:
Estudio de etiología
Límite:
Femenino
/
Humanos
Idioma:
Inglés
Revista:
Arch. endocrinol. metab. (Online)
Asunto de la revista:
Endocrinologia
/
Metabolismo
Año:
2015
Tipo del documento:
Artículo
País de afiliación:
Italia
Institución/País de afiliación:
University of Genoa/IT
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