Heterogenic colonization patterns by Leptospira interrogans in Rattus norvegicus from urban slums
Braz. j. microbiol
;
46(4): 1161-1164, Oct.-Dec. 2015. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-769663
ABSTRACT
Abstract We evaluated the renal colonization by Leptospira interrogans in Rattus norvegicus (rats), as it is the major natural reservoir of urban leptospirosis. We caught 72 R. norvegicus, out of which 32 were found to be positive for L. interrogans by immunofluorescence assay. From these rats, we selected 17 and divided them into six groups based on the mass-age/sex. We performed the immunohistochemistry test against L. interrogans in the kidney sections of the rats and systematically counted the colonized tubules (CTs) in 20 fields. The proportion of positive fields varied from 5% to 95%. The number of CTs in 20 fields varied from 0.5 to 85.5. These differences were not related to age or sex of the animals. The characterization of leptospiral colonization patterns in the natural reservoirs is important to better understand the host-pathogen interactions in leptospirosis.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Enfermedades de los Roedores
/
Variación Genética
/
Genotipo
/
Leptospira interrogans
/
Leptospirosis
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. j. microbiol
Asunto de la revista:
Microbiologia
Año:
2015
Tipo del documento:
Artículo
/
Documento de proyecto
País de afiliación:
Brasil
Institución/País de afiliación:
Fundação Oswaldo Cruz/BR
Similares
MEDLINE
...
LILACS
LIS