Genotyping of multidrug-resistant strains of Pseudomonas aeruginosa isolated from burn and wound infections by ERIC-PCR
Acta cir. bras
;
31(3): 206-211, Mar. 2016. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-777090
ABSTRACT
ABSTRACT PURPOSE:
To determine the genetic diversity of MDR P. aeruginosa strains isolated from burn and wound infections in Ahvaz, Iran, by ERIC-PCR.METHODS:
From total 99 strains of P. aeruginosa defined as MDR by using drug susceptibility testing, 66 were subjected to ERIC-PCR analysis, comprises 53 strains isolated from burn infection, and 13 randomly selected strains from wound infection with higher resistance to combinations of more numbers of drugs.RESULTS:
Eight clusters (I to VIII), and 50 single clones were generated for tested MDR isolates analyzed by ERIC-PCR. The high heterogeneity was observed among the isolates from burn infections including 16 isolates which were categorized in eight clusters and 37 single clones. The isolates in clusters II, III, VI, VIII showed 100% similarity.CONCLUSIONS:
The high level of genotypic heterogeneity in P. aeruginosa strains demonstrated no genetic correlation between them. Extremely high drug resistance in isolates from burn, suggests that efficient control measures and proper antibiotic policy should be observed.
Texto completo:
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Índice:
LILACS (Américas)
Asunto principal:
Pseudomonas aeruginosa
/
Infecciones por Pseudomonas
/
Infección de Heridas
/
Quemaduras
/
ADN Bacteriano
/
Farmacorresistencia Bacteriana Múltiple
Límite:
Humanos
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2016
Tipo del documento:
Artículo
País de afiliación:
Irán
Institución/País de afiliación:
Ahvaz Jundishapur University of Medical Sciences/IR
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