The effects of photobiomodulation therapy on Staphylococcus aureus infected surgical wounds in diabetic rats. A microbiological, histopathological, and biomechanical study
Acta cir. bras
;
31(8): 498-504, Aug. 2016. tab, graf
Artículo
en Inglés
| LILACS
| ID: lil-792412
ABSTRACT
ABSTRACT PURPOSE:
To evaluate the effects of photobiomodulation therapy (PBMT) at 685 nm on diabetic wound healing in rats suffering from bacterial infection induced by Staphylococcus aureus (S. aureus).METHODS:
Thirty streptozotocin-induced diabetic rats were allocated into two groups control and PBMT. A 4-cm full-thickness linear-incision was made on the dorsal midline and was contaminated with S. aureus. The wounds in the PBMT group were irradiated daily for 5 consecutive days, starting 3 days after the induction and always in the mornings.RESULTS:
The result revealed that PBMT resulted in a significant decrease in S. aureus CFU in the PBMT group in comparison to the control group (P<0.05). The length of wounds, in the 2nd and 3rd weeks, in the PBMT group were significantly shorter compared to the control group (P<0.05). PBMT caused a significant increase in the histological parameters in comparison to the control group (P<0.05). Moreover, PBMT significantly increased the breaking strength of the surgical scars produced in the skin of the PBMT group when compared to the control group (P<0.05).CONCLUSION:
Photobiomodulation therapy may be useful in the management of wound infection through a significant bacterial growth inhibition and an acceleration of wound healing process.
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Infecciones Estafilocócicas
/
Infección de la Herida Quirúrgica
/
Cicatrización de Heridas
/
Terapia por Luz de Baja Intensidad
/
Diabetes Mellitus Experimental
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
Cirugía General
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2016
Tipo del documento:
Artículo
País de afiliación:
Irán
Institución/País de afiliación:
Baqiyatallah University of Medical Sciences/IR
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