Vitamin E stimulates endotoxin-inhibited monocyte migration and phagocytosis in vivo
Braz. j. med. biol. res
;
22(11): 1401-3, 1989. ilus
Artículo
en Inglés
| LILACS
| ID: lil-83146
ABSTRACT
Intravenous administration of E. coli endotoxin (LPS, 30 microng/kg, iv) inhibited thioglycollatestimulated accumulation of monocytes into the rat peritoneal cavity, measured 48 and 72 h later, by about 40%. Pretreatment of animals with vitamin E (50 mg/kg, im) restored thioglycollate-induced monocyte migration in LPS-challenged rats to control levels. Vitamin E also partially reversed LPS-induced inhibition of monocyte phagocytosis in vivo. The results suggest that vitamin E could be beneficial in restoring leukocyte function in septicemic states
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Índice:
LILACS (Américas)
Asunto principal:
Cavidad Peritoneal
/
Fagocitosis
/
Vitamina E
/
Inhibición de Migración Celular
/
Monocitos
/
Endotoxinas
/
Escherichia coli
Límite:
Animales
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
1989
Tipo del documento:
Artículo
/
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