Reticulin antibodies: relationship with endocardium-vessel-interstitium antibodies and heterophilic antibodies
Braz. j. med. biol. res
;
23(2): 151-61, 1990. tab, ilus
Artículo
en Inglés
| LILACS
| ID: lil-85152
RESUMO
Indirect immunofluorescence was used to compare reticulin antibodies, endocardium-vessel-interstitium (EVI) antibodies and heterophilic antibodies in serum samples from patients with degenerative and inflammatory diseases, Chagas' disease, or paracoccidioidomycosis and from healthy blood donors. The antigen substrates used were rat, mouse and human liver for reticulin antibodies, mouse and human heart and skeletal muscle for EVI factor, and rat heart and rat, mouse and human kidney and stomach for heterophilic antibodies. The three antibodies produced extremely similar fluorescent patterns and were present simultaneously in a large proportion of reticulin-positive serum samples. The three antibodies were significantly absorbed by heterophilic antigens such as sheep and rat red blood cells and guinea pig kidney, by Trypanosoma cruzi (an antigen associated with EVI factor) and by Paracoccidioides brasiliensis. However, they did not react with several human tissues. These results suggest that reticulin and EVI antibodies can be considered to be heterophilic antibodies
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Índice:
LILACS (Américas)
Asunto principal:
Paracoccidioidomicosis
/
Reticulina
/
Enfermedad de Chagas
/
Anticuerpos
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
1990
Tipo del documento:
Artículo
/
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