Distinct ultrastructural aspects in different biopsies of a single patient with diffuse cutaneous leishmaniasis
Mem. Inst. Oswaldo Cruz
;
85(1): 53-9, jan.-mar. 1990. tab, ilus
Artículo
en Inglés
| LILACS
| ID: lil-85167
ABSTRACT
The authors investigated the relation between parasites and host-cells in active and regressed lesions of a patient with diffuse cutaneous leishmaniasis, evaluating the frequency of different cell types, and the location and integrity of amastigotes. No correlation was found between parasite integrity and size of parasitophorous vacuoles. They observed ultrastructural findings characterizing a cell mediated immune response macrophages lysis, parasitic destruction inside macrophages, close contact between parasitized macrophages and lymphocytes and between parasites and lymphocytes, lymphocytic infiltration and fibrosis. They suggest that in DCL there is a limited cellular immune response, although insufficient to control infection
Texto completo:
Disponible
Índice:
LILACS (Américas)
Asunto principal:
Piel
/
Leishmaniasis
Límite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Mem. Inst. Oswaldo Cruz
Asunto de la revista:
Medicina Tropical
/
Parasitología
Año:
1990
Tipo del documento:
Artículo
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