Effect of turpentine on alfa-1 major acute phase concentration in normal and adrenalectomized rats

ABSTRACT

Acute phase response of plasma alfa-1-major acute phase (alfa1-MAP) was studied in normal and adrenalectomized rats. Alfa1-MAP basal levels were higher in female than in male rats. This proteins, measured by radial immunodiffusion, increased significantly both in male and female rats 24 and 48 h after a turpentine stimulus, proving to be a positive acute phase protein for both sexes. In adrenalectomized male rats the increase of plasma alfa-1MAP concentration was not different from that observed in sham-operated rats, suggesting that the acute phase response of this protein is not corticoid dependent