Effect of amygdaloid kindled seizures during pregnancy on neonatal brain biogenic amines
Braz. j. med. biol. res
; 23(9): 827-30, 1990. ilus
Article
en En
| LILACS
| ID: lil-92404
Biblioteca responsable:
BR26.1
ABSTRACT
The effects of amygdaloid kindled seizures during pregancy on the concentrations of noradrenaline (NE), dopamine (DA) and serotonin (5HT) and of their repective metabolites, 3-methoxy-4-hydroxyphenylglycol (MHPG), normetanephrine (NMN), homovanilic acid (HVA) and 5-hydroxy-indoleacetic acid (5HIAA), have been studied in the cerebral cortex, brain stem and cerebellum of rat offspring at bith. The levels of DA and NE were invreased and those of HVA and MHPG wee not modified in the cortex. The levels of DA, NE, 5HT, MHPG and 5HIAA were increased in the cerebellum. The brain stem presented a decrease in DA and 5HT levels, but increased MHPG and HVA levels. It is suggested that, in order to investigate possible changes in the biogenic amine loevels on the postnatal period, carefully planned prospective studies are needed
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Índice:
LILACS
Asunto principal:
Convulsiones
/
Aminas Biogénicas
/
Encéfalo
/
Catecolaminas
/
Epilepsia
/
Cerebro
/
Amígdala del Cerebelo
/
Excitación Neurológica
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Animals
/
Pregnancy
Idioma:
En
Revista:
Braz. j. med. biol. res
Asunto de la revista:
BIOLOGIA
/
MEDICINA
Año:
1990
Tipo del documento:
Article
/
Congress and conference