Age-associated changes of memory (CD45RO+) and naive (CD45R+) T cells
Braz. j. med. biol. res
;
24(3): 275-9, mar. 1991. tab
Artículo
en Inglés
| LILACS
| ID: lil-99565
ABSTRACT
The total number of lymphocytes and the percentage of CD45RO+ (putative memory T cell) and CD45R+ (putative naive T cell) were determined in 15 cord blod samples, 66 healthy children ranging in a age from 1 to 18 years, 16 adults (23-59 years) and 16 aged individuals (60-96 years). The total number of lymphocytes decreased with age and reached the adult range in children to the adult group,white the percentage of CD45RO+ Tcells was low in cord blood and increased with age.No significant difference was observed between the adult and the aged groups for either lymphocyte subset. These data support the view that CD45RO+ and CD45R+ T-cell subsets represent maturational stages of T cells
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Índice:
LILACS (Américas)
Asunto principal:
Envejecimiento
/
Linfocitos T
/
Antígenos CD
/
Subgrupos de Linfocitos T
/
Antígenos de Histocompatibilidad
Tipo de estudio:
Factores de riesgo
Límite:
Adolescente
/
Adulto
/
Aged80
/
Niño
/
Child, preschool
/
Humanos
/
Lactante
Idioma:
Inglés
Revista:
Braz. j. med. biol. res
Asunto de la revista:
Biologia
/
Medicina
Año:
1991
Tipo del documento:
Artículo
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