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Cytomorphological features, AgNOR counts and c-erb B-2 in carcinoma breast.
J Indian Med Assoc ; 1998 Mar; 96(3): 71-3, 76
Artículo en Inglés | IMSEAR | ID: sea-105304
ABSTRACT
The present study was designed to evaluate the cytomorphological features (nuclear grade and smear pattern) and AgNOR counts in 60 cases of carcinoma breast. The smears were stained with May Gruenwald Giemsa (MGG) and Papanicolaou stains. Silver staining nucleolar organiser region (AgNOR) counts and c-erb B-2 immunostaining were also done in each case. The smear pattern was assessed and classified as 'typical', 'cluster predominant' or 'individual cell type', and the nuclei were graded as grade I, II or III. Smear pattern and nuclear grade were found to be related variables. A significant association was found between nuclear grade and AgNOR counts (p = 0.03). Also postmenopausal women had statistically significant higher nuclear grades and less cohesive cell clusters as compared to premenopausal women. Twenty-three carcinoma breast were positive for c-erb B-2, of these 14 were postmenopausal women.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Pronóstico / Biopsia con Aguja / Neoplasias de la Mama / Anciano / Femenino / Humanos / Biomarcadores de Tumor / Estudios Prospectivos / Posmenopausia / Carcinoma Ductal de Mama Tipo de estudio: Estudio observacional / Estudio pronóstico Idioma: Inglés Revista: J Indian Med Assoc Año: 1998 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Pronóstico / Biopsia con Aguja / Neoplasias de la Mama / Anciano / Femenino / Humanos / Biomarcadores de Tumor / Estudios Prospectivos / Posmenopausia / Carcinoma Ductal de Mama Tipo de estudio: Estudio observacional / Estudio pronóstico Idioma: Inglés Revista: J Indian Med Assoc Año: 1998 Tipo del documento: Artículo