Neuropharmacological actions of some newly synthesized Mannich bases.
Indian J Physiol Pharmacol
;
1981 Jul-Sep; 25(3): 269-73
Artículo
en Inglés
| IMSEAR
| ID: sea-106206
ABSTRACT
Benzamido (alkyl) methyl pyrrolidine Mannich bases were synthetized and subjected to certain neuropharmacological studies. All the bases reduced the pentobarbitone sleeping time and rota-rod grip of rats. The Mannich bases II, III and V raised the minimal electro-shock seizure threshold of rats. The TAB-induced pyrexia was not reduced by the bases I and III in rabbits. None of the bases showed any significant analgesic activity.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Pentobarbital
/
Conejos
/
Ratas
/
Receptores de Droga
/
Umbral Sensorial
/
Sueño
/
Factores de Tiempo
/
Temperatura Corporal
/
Encéfalo
/
Masculino
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1981
Tipo del documento:
Artículo
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