Contraceptive efficacy of Depot Provera jet-injected into the cervix.

Riar, S S; Sawhney, R C; Thomas, P; Bardhan, J; Kain, A K; Singh, T

Riar, S S; Sawhney, R C; Thomas, P; Bardhan, J; Kain, A K; Singh, T.

Indian J Physiol Pharmacol ; 1991 Jan; 35(1): 21-6

Artículo en Inglés | IMSEAR | ID: sea-106267

ABSTRACT

ABSTRACT

Depot-medroxy progesterone acetate (DMPA) was jet deposited into the uterus/cervix of rats, rabbits and rhesus monkeys with the help of a modified jet injection apparatus. Since the drug was delivered under pressure, it was distributed deep into the muscular layers around the place of deposition. After one deposition the drug acted as an effective contraceptive for a period of three months. The merits of this delivery technique are discussed.

Asunto(s)

Animales; Cuello del Útero; Anticonceptivos Femeninos/administración & dosificación; Femenino; Hormona Folículo Estimulante/sangre; Inyecciones a Chorro; Hormona Luteinizante/sangre; Macaca mulatta; Masculino; Medroxiprogesterona/administración & dosificación; Acetato de Medroxiprogesterona; Embarazo; Progesterona/sangre; Conejos; Ratas

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Progesterona / Conejos / Ratas / Femenino / Masculino / Embarazo / Inyecciones a Chorro / Hormona Luteinizante / Cuello del Útero / Acetato de Medroxiprogesterona Idioma: Inglés Revista: Indian J Physiol Pharmacol Año: 1991 Tipo del documento: Artículo

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