Evaluation of antimuscarinic activity in human volunteers: a teaching aid in clinical pharmacology.
Indian J Physiol Pharmacol
;
1995 Apr; 39(2): 163-5
Artículo
en Inglés
| IMSEAR
| ID: sea-106463
ABSTRACT
The antimuscarinic activity of oxyphenonium bromide, diphenhydramine hydrochloride and astemizole were evaluated in six volunteers. The parameters used were salivary secretion, heart rate and pupillary size. The results indicated that the changes in heart rate and pupillary size and measurements were not convenient parameters for class room demonstration. However, salivary secretion and dryness of mouth were found to be reliable parameters for measurement. It was concluded that simple procedures like evaluation of antimuscarinic activity could be introduced as teaching aids in clinical pharmacology for undergraduate students.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Salivación
/
Estudiantes de Medicina
/
Humanos
/
Masculino
/
Pupila
/
Astemizol
/
Oxifenonio
/
Antagonistas Muscarínicos
/
Adulto
/
Difenhidramina
Tipo de estudio:
Ensayo Clínico Controlado
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1995
Tipo del documento:
Artículo
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