Danazol-induced biochemical changes in the rat ovary.
Indian J Physiol Pharmacol
;
1998 Apr; 42(2): 252-8
Artículo
en Inglés
| IMSEAR
| ID: sea-106569
ABSTRACT
Effect of varying doses of danazol, a synthetic steroid derivative of 17 alpha-ethinyl testosterone has been observed on the biochemistry of the rat ovary. Biochemically total proteins decreased and total lipids increased with the danazol treatment. Triglycerides, the stored form of lipids formed the major components of lipids in the treated ovaries. The amount of phospholipids, glycolipids, cholesterol and free fatty acids decreased in the ovaries with increased danazol treatment. The functional significance of these changes have been discussed with ovarian physiology especially in relation to follicular growth and atresia.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ovario
/
Fosfolípidos
/
Ratas
/
Femenino
/
Glucolípidos
/
Ratas Wistar
/
Danazol
/
Relación Dosis-Respuesta a Droga
/
Antagonistas de Estrógenos
/
Ácidos Grasos no Esterificados
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1998
Tipo del documento:
Artículo
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