Anti-inflammatory and analgesic properties of four amino-acids.
Indian J Physiol Pharmacol
;
1984 Oct-Dec; 28(4): 299-305
Artículo
en Inglés
| IMSEAR
| ID: sea-106657
ABSTRACT
Orally administered L-isoleucine, DL-isoleucine and L-leucine exhibited anti-inflammatory activity in many test models of inflammation except formaldehyde-induced inflammation. L-beta-phenylalanine inhibited carrageenan-induced oedema only. L-isoleucine also exhibited prolonged analgesic effect while DL-isoleucine had a short lasting effect. The amino-acids produced no gastric ulceration or overt acute toxicity in doses which effectively suppress inflammation. Anti-inflammatory activity seems to be related with interference with the action and/or synthesis of prostaglandins and deserves further intensive study.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Femenino
/
Masculino
/
Carragenina
/
Fenilbutazona
/
Antiinflamatorios no Esteroideos
/
Diarrea
/
Edema
/
Aminoácidos
/
Granuloma
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1984
Tipo del documento:
Artículo
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