Arrest reaction with concomitant spike and wave afterdischarge following thalamic stimulation in conscious juvenile monkeys with Al (OH)3 focal premotor lesions.

ABSTRACT

The behavioural and electroencephalographic responses resulting from stimulation of a specific area in the nucleus medialis dorsalis (nMD) of unanaesthetized juvenile Rhesus monkeys is described. A behavioural arrest reaction, lack of awareness and motor inhibition with concomitant 2 1/2 to 3Hz spike and wave EEG afterdischarge patterns were obtained by stimulation of the nMD in monkeys with bilaterally symmetrical aluminium hydroxide Al (OH)3 lesions in anterior premotor cortical areas.