Protective effect of curcumin during selenium induced toxicity on dehydrogenases in hepatic tissue.
Indian J Physiol Pharmacol
;
2005 Jan; 49(1): 111-4
Artículo
en Inglés
| IMSEAR
| ID: sea-107285
ABSTRACT
Selenium administration resulted in a marked decrease in the activity levels of the liver succinate dehydrogenase, malate dehydrogenase, and lactate dehydrogenase while pyruvate dehydrogenase increased significantly (P<0.001) in the wistar rat. The degree of decrease of these enzymes was significantly less (P<0.001) when rats were treated with curcumin, a natural constituent Curcuma longa. Curcumin seems to prevent oxidative damage mediated through selenium and protect the dehydrogenases possibly through its anti-oxidative property.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Selenio
/
Succinato Deshidrogenasa
/
Masculino
/
Administración Oral
/
Ratas Wistar
/
Curcumina
/
Inhibidores Enzimáticos
/
L-Lactato Deshidrogenasa
/
Hígado
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
2005
Tipo del documento:
Artículo
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