Antagonism of bromocriptine-induced cage climbing behaviour in mice by the selective D-2 dopamine receptor antagonists, metoclopramide and molindone.
Indian J Physiol Pharmacol
;
1986 Jan-Mar; 30(1): 85-90
Artículo
en Inglés
| IMSEAR
| ID: sea-107291
ABSTRACT
Bromocriptine (5-30 mg/kg, ip), 2 hr after administration, induced cage climbing behaviour in mice. Pretreatment with haloperidol, an antagonist of both D-1 and D-2 dopamine receptors, metoclopramide and molindone, the selective D-2 dopamine receptor antagonists, effectively antagonised bromocriptine-induced climbing behaviour. The results indicate that bromocriptine most probably induces climbing behaviour in mice by stimulating the postsynaptic striatal D-2 dopamine receptors.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Conducta Animal
/
Masculino
/
Bromocriptina
/
Receptores Dopaminérgicos
/
Receptores de Dopamina D2
/
Relación Dosis-Respuesta a Droga
/
Haloperidol
/
Animales
/
Metoclopramida
/
Ratones
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1986
Tipo del documento:
Artículo
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