Toxicological study of Semecarpus anacardium nut extract.
Indian J Physiol Pharmacol
;
1979 Apr-Jun; 23(2): 115-20
Artículo
en Inglés
| IMSEAR
| ID: sea-107457
ABSTRACT
Toxicological study was carried out in rats with chloroform-soluble fraction of the nuts of Semecarpus anacardium to determine its safe non-toxic dose. The fraction produced toxicity at all levels tested (50-400 mg/kg) but the extent of toxicity was found dose-dependent. At lower doses this fraction induced partial growth inhibition over 36 days and higher doses proved fatal within 6 days. It was observed that 230 mg/kg caused 50% mortality in rats and this value is 1380 mg/m2 when expressed for body surface area. This work will be of some use in the cancer chemotherapy study of the fraction.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Plantas Medicinales
/
Ratas
/
Factores de Tiempo
/
Conducta Animal
/
Peso Corporal
/
Masculino
/
Extractos Vegetales
/
Dosificación Letal Mediana
/
Animales
/
Nueces
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1979
Tipo del documento:
Artículo
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