Effects of nitroxazepine on diastolic blood pressure in mild hypertensive patients--a short term clinical study.
Indian J Physiol Pharmacol
;
1995 Jul; 39(3): 293-5
Artículo
en Inglés
| IMSEAR
| ID: sea-107778
ABSTRACT
In a double blind short term clinical study, nitroxazepine has been found to be superior over placebo in reducing the diastolic blood pressure in mild hypertensive patients. In short term open clinical trial design nitroxazepine (25 mg PO, HS) has been found to be superior and better tolerated than diazepam (5 mg PO, HS). In open clinical trial design, nitroxazepine (25 mg PO, HS) reduced the diastolic blood pressure to the target level (100 mm Hg and less) effectively controlling the uncontrolled hypertensive patients receiving maintenance dose of beta blockers. There was no such beneficial effect in patients receiving maintenance doses of other antihypertensive drugs (pilot study). Adverse drug reactions like disturbed sleep in one, uneasiness in 3, palpitation in one and dryness of mouth in one patient have been observed.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Presión Sanguínea
/
Humanos
/
Proyectos Piloto
/
Método Doble Ciego
/
Antagonistas Adrenérgicos beta
/
Adulto
/
Diazepam
/
Dibenzoxazepinas
/
Hipertensión
/
Antihipertensivos
Tipo de estudio:
Ensayo Clínico Controlado
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1995
Tipo del documento:
Artículo
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