A preliminary report on the antiarrhythmic action of some newly synthesized glutarimide compounds.

Patel, N B; Jindal, M N; Patel, V K

Patel, N B; Jindal, M N; Patel, V K.

Indian J Physiol Pharmacol ; 1976 Jul-Sep; 20(3): 172-6

Artículo en Inglés | IMSEAR | ID: sea-107919

ABSTRACT

ABSTRACT

The effects of a new series of glutarimide compounds have been studied in acetylcholine induced auricular fibrillation in anaesthetized cats and epinephrine induced ventricular arrhythmmias in conscious pigeons. Some of the compounds showed varying degree of protective action against experimental arrhythmias. However these compounds were found to be less potent than quinidine. The mechanism of antiarrhythmic action has been discussed.

Asunto(s)

Acetilcolina; Anestesia Local; Animales; Antiarrítmicos/uso terapéutico; Fibrilación Atrial/inducido químicamente; Gatos; Columbidae; Epinefrina; Femenino; Cobayas; Imidas/uso terapéutico; Masculino; Piperidinas/uso terapéutico; Piperidonas/uso terapéutico; Conejos; Fibrilación Ventricular/inducido químicamente

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Columbidae / Piperidinas / Piperidonas / Conejos / Fibrilación Atrial / Fibrilación Ventricular / Femenino / Masculino / Acetilcolina / Epinefrina Tipo de estudio: Estudio diagnóstico Idioma: Inglés Revista: Indian J Physiol Pharmacol Año: 1976 Tipo del documento: Artículo

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