Effect of gold thiomalate on cell proliferation and collagen synthesis of synovial cells in culture.
Indian J Physiol Pharmacol
;
1987 Oct-Dec; 31(4): 245-9
Artículo
en Inglés
| IMSEAR
| ID: sea-108084
ABSTRACT
Human synovial cells from cases of rheumatoid and osteoarthritis were cultured and at their 3-5 passages, were treated with gold thiomalate. At early-log phase gold thiomalate arrested the proliferation of cells. However, at confluent state shere was a slight proliferation of synovial cells. This was followed by an increase in prolyl hydroxylase, collagen and protein synthesis, indicating that gold salts directly stimulate the synovial cells.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Artritis Reumatoide
/
Membrana Sinovial
/
Humanos
/
División Celular
/
Células Cultivadas
/
Colágeno
/
Tiomalato Sódico de Oro
/
Procolágeno-Prolina Dioxigenasa
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1987
Tipo del documento:
Artículo
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