Effects of cimetidine combination with cyclophosphamide in transplanted murine tumors.
Indian J Physiol Pharmacol
;
1989 Jul-Sep; 33(3): 171-4
Artículo
en Inglés
| IMSEAR
| ID: sea-108415
ABSTRACT
Studies were carried out on the combination of Cimetidine (CMTD) with Cytoxan (CTX) in three murine tumors. While the combination significantly potentiated the anticancer effect of CTX in L1210 leukemia, the results with P388 leukemia were not significantly different. The results with Lewis Lung Carcinoma showed a consistent reduction in the number of metastases. However, there was no consistent concomitant prolongation in survival. The host strain, biology of the tumour and the drug used in combination with CMTD might be some of the factors responsible for the varied response.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Femenino
/
Masculino
/
Leucemia Experimental
/
Leucemia L1210
/
Leucemia P388
/
Cimetidina
/
Ciclofosfamida
/
Quimioterapia Combinada
/
Neoplasias Pulmonares
/
Animales
Tipo de estudio:
Estudio pronóstico
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1989
Tipo del documento:
Artículo
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