Effect of Septilin--a herbal preparation on pharmacokinetics of carbamazepine in rabbits.
Indian J Physiol Pharmacol
;
1998 Oct; 42(4): 527-32
Artículo
en Inglés
| IMSEAR
| ID: sea-108499
ABSTRACT
The study was carried out in rabbits, to see the effects of Septilin, a herbal preparation on the single and multiple dose kinetics of carbamazepine. Single dose treatment of Septilin significantly decreased t 1/2a. t 1/2e. AUCo-alpha of carbamazepine. Steady state Cmax and AUC0-24 of carbamazepine were also reduced significantly in comparison to those of control rabbits after 7 days co-administration of Septilin. We conclude that Septilin decrease/hinder the absorption process of carbamazepine through an unknown mechanism.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Conejos
/
Masculino
/
Carbamazepina
/
Extractos Vegetales
/
Antiinflamatorios no Esteroideos
/
Interacciones Farmacológicas
/
Animales
/
Anticonvulsivantes
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1998
Tipo del documento:
Artículo
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