Enhanced platelet aggregation by oral contraceptives: effect of PG synthetase inhibitors.
Indian J Physiol Pharmacol
;
1982 Jul-Sep; 26(3): 231-4
Artículo
en Inglés
| IMSEAR
| ID: sea-108501
ABSTRACT
Platelet aggregation time was significantly (P less than 0.01) decreased in female rabbits treated with oral contraceptive (a preparation containing low dose of estrogen) as also by injection of diethylstilbestrol (10 mg/kg), while in animals that received indomethacin (10 mg/kg) or aspirin (30 mg/kg) (PG synthetase inhibitors) along with oral contraceptives or diethylstilbestrol there was no significant alteration in platelet aggregation time. The increased synthesis of prostaglandins or some of the intermediary product like TXA2 might be responsible for this effect.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Conejos
/
Femenino
/
Agregación Plaquetaria
/
Aspirina
/
Indometacina
/
Inhibidores de la Ciclooxigenasa
/
Anticonceptivos Orales
/
Anticonceptivos Orales Combinados
/
Anticonceptivos Hormonales Orales
/
Anticonceptivos Secuenciales Orales
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1982
Tipo del documento:
Artículo
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