Pharmacological effects of Azadirachta indica (neem) leaf extract on the ECG and blood pressure of rat.
Indian J Physiol Pharmacol
;
1994 Jul; 38(3): 223-5
Artículo
en Inglés
| IMSEAR
| ID: sea-108692
ABSTRACT
Neem leaf alcoholic extract (NLE) was investigated for its effects on the ECG and blood pressure of rat. Intravenous administration of NLE (100, 300 and 1000 mg/kg) resulted in initial bradycardia followed by cardiac arrhythmia in rats. NLE produced a significant and dose-related fall in blood pressure which was immediate, sharp and persistent. Pre-treatment with either atropine or mepyramine failed to prevent the hypotensive effect of NLE.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Arritmias Cardíacas
/
Ratas
/
Presión Sanguínea
/
Determinación de la Presión Sanguínea
/
Bradicardia
/
Masculino
/
Extractos Vegetales
/
Hojas de la Planta
/
Etanol
/
Relación Dosis-Respuesta a Droga
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1994
Tipo del documento:
Artículo
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