Synthesis and in vivo hypoglycemic screening studies on some life essential metal complexes of oral antidiabetic [N-(p-tolylsulphonyl)-N'-n butyl-urea] (tolbutamide).
Indian J Physiol Pharmacol
;
1995 Apr; 39(2): 166-8
Artículo
en Inglés
| IMSEAR
| ID: sea-108715
ABSTRACT
Present communication deals with the synthesis of complexes of [N-(p-tolylsulphonyl)-N'-n butyl-urea], with certain transition metals viz. Cu(II), Zn(II), Fe(II) and Cd(II). Structures of all the complexes have been established on the basis of their consistent elemental and spectral analysis. Also, it reports their in vivo hypoglycemic screening on albino rats. Out of all the complexes studied, Zn-Tolbutamide complex could be recommended as more potent hypoglycemic agent in lieu of tolbutamide alone.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Espectrofotometría Infrarroja
/
Tolbutamida
/
Zinc
/
Cadmio
/
Administración Oral
/
Cobre
/
Sinergismo Farmacológico
/
Hipoglucemia
/
Hierro
Tipo de estudio:
Estudio diagnóstico
/
Estudio de tamizaje
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1995
Tipo del documento:
Artículo
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