Uterotropic effect of clofibrate and phenylbutazone in immature female rats.
Indian J Physiol Pharmacol
;
1982 Apr-Jun; 26(2): 147-51
Artículo
en Inglés
| IMSEAR
| ID: sea-108729
ABSTRACT
The uterotropic effect of clofibrate and phenylbutazone was studied in immature female rats. A significant increase in the uterine wet weight was observed following clofibrate and phenylbutazone administration. Clofibrate but not phenylbutazone synergized with the uterotropic effect of ethinyl-oestradiol. Phenylbutazone pretreatment significantly decreased the pentobarbitone sleeping time. The uterotropic effect of clofibrate and phenylbutazone might involve displacement of 17-beta oestradiol (or ethinyl oestradiol) from plasma albumin binding sites in rats.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Tamaño de los Órganos
/
Pentobarbital
/
Ratas
/
Sueño
/
Útero
/
Femenino
/
Fenilbutazona
/
Clofibrato
/
Sinergismo Farmacológico
/
Estrógenos
Idioma:
Inglés
Revista:
Indian J Physiol Pharmacol
Año:
1982
Tipo del documento:
Artículo
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