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Influence of calcium removal from bath solution on isolated rat duodenum contractions.
Indian J Physiol Pharmacol ; 1992 Jul; 36(3): 181-4
Artículo en Inglés | IMSEAR | ID: sea-108988
ABSTRACT
In this study whether extracellular Ca++ is essential to produce an increase of tension of isolated rat duodenum by ACh, 5-HT, AVP and KCl-, was examined. KCl- and AVP-evoked contractions were almost totally prevented by Ca++ removal from bath solution. The increase of tension of isolated duodenum caused by ACh or 5-HT was totally prevented after adding nifedipine, a Ca++ channel blocker, into Ca free solution. Our results suggest that ACh or 5-HT utilizes intracellular as well as extracellular sources of Ca++ to produce contraction in rat duodenum, whereas AVP-or KCl evoked contraction was mainly due to influx of Ca from extracellular sources.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Cloruro de Potasio / Ratas / Arginina Vasopresina / Nifedipino / Acetilcolina / Serotonina / Calcio / Duodeno / Animales / Contracción Muscular Idioma: Inglés Revista: Indian J Physiol Pharmacol Año: 1992 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Cloruro de Potasio / Ratas / Arginina Vasopresina / Nifedipino / Acetilcolina / Serotonina / Calcio / Duodeno / Animales / Contracción Muscular Idioma: Inglés Revista: Indian J Physiol Pharmacol Año: 1992 Tipo del documento: Artículo